202207262246

Status:

Tags: haematology

Transfusion

PBM

Blood product

Typical Intraoperative Use Product Source Coagulation Factors Present
Fibrinogen Replacement Fibrinogen Concentrate Human Plasma Fibrinogen, may contain FXIII
Fibrinogen Replacement Cryoprecipitate Human Plasma Fibrinogen, Factors VII, XIII, vWF, Fibronectin
Replacement of coagulation factors for deficiency and/or dysfunction; Warfarin reversal PCC Human Plasma Four-factor contain II, VII, IX, X, Protein C and S, heparin
Three-factor contain II, IX, X, Protein C and S, heparin
Replacement of coagulation factors for deficiency and/or dysfunction Plasma Human Plasma Volume, all the clotting factors, albumin, fibrinogen (not adequate for fibrinogen replacement by itself), Proteins C, S, TFPI
Intractable Coagulopathy despite normalization of coagulation labs Recombinant Activated Factor VII Recombinant (Cell Lines) ../../pages/Factor VIIa

massive transfusion protocol
Transfusion in Paeds

Transfusion reactions


References

Webinar: Haemostasis management in the perioperative period: Old habits die hard

Magic in a Bottle A Focused Review of Factor Concentrates for the Intraoperative Treatment of Acquired Coagulopathy – Fibrinogen Concentrate, Prothrombin Complex Concentrate, and Recombinant Activated Factor VII - BPRCA